Can Depression Cause Loss of Memory[Forgetfulness]?

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Munira Electricwala
Psychologist | Researcher | Psychological Scientist | Writer
14 Sep 20244 min read
A lady id trying to remember and confused with many things like  is memory loss a sign of depression - mave health

The Impact of Depression on Memory: Exploring the Connection

Depression and memory loss are two interconnected issues that can significantly impact an individual's quality of life. While the relationship between these two conditions is complex, research has shown that depression can lead to various types of memory impairment, particularly in short-term memory. In this article, we will explore the connection between depression and memory loss, and discuss the potential impact on an individual's overall well-being.

Understanding Memory Loss and Depression by Definition

Memory loss refers to the inability to recall information, events, or experiences that were previously known. This can range from mild forgetfulness to severe impairment, depending on the underlying cause. 

Depression, on the other hand, is a mental health condition characterised by persistent feelings of sadness, hopelessness, and loss of interest in daily activities.

Can Depression Cause Memory Loss?

Yes, depression can contribute to memory loss. Studies have shown that individuals with depression often experience difficulties in recalling details, concentrating, and making decisions. This is due to the persistent low mood and chronic stress associated with depression, which can affect the brain's structure and function, leading to problems with memory.

Recent Research Findings on the Connection Between Depression and Memory Loss

Several studies have explored the link between depression and memory loss:

  1. A study found a connection between long-term sadness (major depressive disorder) and issues with thinking skills like memory, attention, and decision-making. The researchers discovered that people who experience prolonged periods of depression might struggle with these cognitive skills.
  2. A meta-analysis of magnetic resonance imaging (MRI) brain scans found that people with major depressive disorder had, on average, smaller hippocampal volumes than their non-depressed peers. The hippocampus is one of several brain regions responsible for controlling and managing memory.
  3. Research has shown that depression can affect a person's long-term memory even when other symptoms go into remission. This suggests that the impact of depression on memory can be long-lasting.
  4. A 2010 study found that people with depression showed impairments in working memory, such as the ability to remember visual and spatial information in the short term.
  5. Researchers in a 2013 study discovered that people with depression couldn't identify objects on a screen that were identical or similar to an object they had seen previously, suggesting that memory can be diminished as a result of depression.

Symptoms of Depression to check. This will help you understand when to seek help:

Emotional Symptoms

•⁠  ⁠Persistent Sadness: A continuous feeling of sadness or emptiness.

•⁠  ⁠Irritability: Increased frustration or anger over minor issues.

•⁠  Feelings of Hopelessness: A belief that things will never get better.

•⁠  ⁠Guilt or Worthlessness: Excessive feelings of guilt or a sense of being a failure.

Physical Symptoms:

•⁠  ⁠Changes in Appetite: Significant weight loss or gain, or changes in eating habits.

•⁠  ⁠Sleep Disturbances: Insomnia or sleeping too much.

•⁠  ⁠Fatigue: A constant feeling of tiredness or lack of energy.

•⁠  ⁠Aches and Pains: Unexplained physical symptoms, such as headaches or digestive issues.

Cognitive Symptoms

•⁠  ⁠Difficulty Concentrating: Trouble focusing, making decisions, or remembering things.

•⁠  ⁠Negative Thinking: A tendency to dwell on negative thoughts or events.

Behavioral Symptoms 

•⁠  ⁠Withdrawal from Social Activities: Avoiding friends, family, and previously enjoyed activities.

•⁠  ⁠Decreased Performance: A decline in work or academic performance.

If you are struggling with memory loss or depression, it is crucial to seek professional help and explore the best treatment options for your specific needs. With the right support and strategies, managing these conditions and improving your overall quality of life is possible.

Check out Mave Health’s 12-week program which is clinically proven to deliver measurable and long-lasting results for individuals struggling with such issues.

Conclusion

Depression and memory loss are complex issues that can significantly impact an individual's well-being. While research has shown a clear connection between depression and various types of memory impairment, it is essential to remember that each person's experience is unique.

References

  1. Dillon, D. G., & Pizzagalli, D. A. (2018). Mechanisms of Memory Disruption in Depression. Trends in Neurosciences, 41(3), 137–149. https://doi.org/10.1016/j.tins.2017.12.006
  2. Dodiya, M. (2024, August 28). Can Depression Cause Memory Loss? Because I am Losing my Memory. MAVE HEALTH PRIVATE LIMITED. https://www.mavehealth.com/blogs/can-depression-cause-memory-loss
  3. Gotlib, I. H., & Joormann, J. (2010). Cognition and Depression: Current Status and Future Directions. Annual Review of Clinical Psychology, 6(1), 285–312. https://doi.org/10.1146/annurev.clinpsy.121208.131305
  4. Koolschijn, P. C. M., Van Haren, N. E., Lensvelt‐Mulders, G. J., Pol, H. E. H., & Kahn, R. S. (2009). Brain volume abnormalities in major depressive disorder: A meta‐analysis of magnetic resonance imaging studies. Human Brain Mapping, 30(11), 3719–3735. https://doi.org/10.1002/hbm.20801
  5. Remes, O., Mendes, J. F., & Templeton, P. (2021). Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature. Brain Sciences, 11(12), 1633. https://doi.org/10.3390/brainsci11121633
  6. Scaccia, A. (2019, September 13). Can Depression Cause Memory Loss? Healthline. https://www.healthline.com/health/depression/depression-and-memory-loss.
  7. Villines, Z. (2023, September 20). Are depression and memory loss connected? https://www.medicalnewstoday.com/articles/depression-and-memory-loss
  8. Image Designed by Freepik
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