Do Mood Stabilizers Help With Anxiety?

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Munira Electricwala
Psychologist | Researcher | Psychological Scientist | Writer
11 Oct 20245 min read
Close up hands holding tennis balls with differnet mood drawn on balls - Do Mood Stabilizers Help With Anxiety?

Introduction: Do Mood Stabilizers Hold the Secret to Conquering Anxiety?

Mood stabilizers are often discussed in the context of managing mood disorders, but their role in treating anxiety is complex and nuanced. This article explores whether mood stabilizers can effectively alleviate anxiety symptoms, examining research findings and clinical insights.

Understanding Mood Stabilizers & Anxiety by Definition

Mood stabilizers are a class of medications primarily used to treat bipolar disorder and other mood-related conditions. They work by balancing neurotransmitters in the brain, which can help stabilize mood fluctuations. Common examples include lithium, valproate, and lamotrigine. These medications are believed to influence emotional regulation, potentially benefiting individuals experiencing anxiety alongside mood disorders.

Anxiety disorders are a group of mental health conditions marked by excessive fear or worry that is disproportionate to the actual threat posed. These disorders can manifest in various forms, including generalized anxiety disorder (GAD), panic disorder, social anxiety disorder, and specific phobias. They often lead to significant distress and impairment in social, occupational, or other important areas of functioning.

Can Mood Stabilizers Help in Improving Anxiety?

The answer is maybe. While some individuals may experience relief from anxiety symptoms through the use of mood stabilizers, their effectiveness can vary based on individual circumstances, including the type of anxiety disorder and the presence of other mental health conditions.

Research Findings on How Do Mood Stabilizers Help in Improving Anxiety?

Research indicates that mood stabilizers can play a role in managing anxiety, particularly when it coexists with mood disorders. Here are some key findings:

Neurotransmitter Regulation: Mood stabilizers like lamotrigine and valproate may enhance GABAergic activity, which can reduce anxiety symptoms by promoting a calming effect on the nervous system.

Clinical Trials: Studies (2023) have shown that certain mood stabilizers can significantly reduce anxiety levels in patients with bipolar disorder. For instance, valproate has demonstrated efficacy in treating anxiety symptoms even in individuals without bipolar disorder.

Combination Therapy: Mood stabilizers are often more effective when used alongside other treatments, such as antidepressants or psychotherapy. This combination approach addresses both mood stabilization and anxiety reduction.

What’s the Success Rate of Mood Stabilizers in Improving Anxiety?

The success rate of mood stabilizers for anxiety improvement varies widely:

Studies Suggesting Positive Outcomes: Research indicates that medications like lamotrigine can significantly reduce emotional processing biases associated with anxiety. Valproate has shown robust evidence for reducing anxiety symptoms in both bipolar and non-bipolar patients.

Studies Suggesting Limited Impact: Some studies (2020) have found that not all mood stabilizers effectively reduce anxiety; for instance, certain atypical antipsychotics may worsen anxiety symptoms rather than alleviate them. The effectiveness of mood stabilizers can be influenced by individual differences in response to medication.

Mixed Results: Overall, while there is promising evidence supporting the use of mood stabilizers for anxiety management, results are not universally positive, indicating a need for personalized treatment plans.

Symptoms of Anxiety to check. This will help you understand when to seek help:

Symptoms of anxiety can vary widely among individuals and may include both psychological and physical manifestations:

Psychological Symptoms:

•⁠  ⁠Excessive Worry: Persistent concerns about everyday issues.

•⁠  ⁠Restlessness: Feeling on edge or unable to relax.

•⁠  ⁠Difficulty Concentrating: Trouble focusing on tasks or making decisions.

•⁠  ⁠Irritability: Increased sensitivity or frustration.

•⁠  ⁠Sleep Disturbances: Difficulty falling asleep or staying asleep.

Physical Symptoms:

•⁠  ⁠Panic Attacks: Sudden episodes of intense fear that may include heart palpitations, shortness of breath, sweating, trembling, or feelings of impending doom.

•⁠  ⁠Muscle Tension: Chronic tightness in muscles leading to discomfort.

•⁠  ⁠Gastrointestinal Issues: Nausea or stomachaches.

•⁠  ⁠Hyperventilation: Rapid breathing that may lead to dizziness or light-headedness.

•⁠  ⁠Cold or Sweaty Extremities: Numbness or tingling sensations in hands or feet.

These symptoms can be debilitating and often lead individuals to avoid situations that trigger their anxiety. If untreated, anxiety disorders can significantly impact quality of life and overall well-being.

For those seeking a comprehensive approach to mental health, Mave Health offers personalized programs that integrate therapy and lifestyle changes to support overall well-being. Always consult your healthcare provider for guidance on the best treatment options for your specific situation.

Do Read More About Anxiety

  1. How to Help Someone with Anxiety: A Guide for Supportive Friends and Family
  2. Reduce Anxiety immediately with other 12 Effective ways along with 333 Rule
  3. How to Treat Anxiety Without Medication?
  4. How Do Psychiatrists Treat Anxiety Disorders?
  5. 5-4-3-2-1 Grounding Technique Exercise
  6. tDCS Device For Anxiety
  7. Foods to Fight Anxiety

Conclusion

In summary, while mood stabilizers can help manage anxiety for some individuals, their effectiveness is not guaranteed and varies based on personal health profiles. It’s crucial for anyone considering these medications to consult with a healthcare provider to explore tailored treatment options.

References

  1. Carli, M., Weiss, F., Grenno, G., Ponzini, S., Kolachalam, S., Vaglini, F., Viaggi, C., Pardini, C., Tidona, S., Longoni, B., Maggio, R., & Scarselli, M. (2023). Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics. Current Neuropharmacology, 21(4), 935–950. https://doi.org/10.2174/1570159x21666230224102318
  2. Cipriani, A., Reid, K., Young, A. H., Macritchie, K., & Geddes, J. (2013). Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder. Cochrane Library. https://doi.org/10.1002/14651858.cd003196.pub2
  3. Costa, B., & Vale, N. (2023). Understanding Lamotrigine’s Role in the CNS and Possible Future Evolution. International Journal of Molecular Sciences, 24(7), 6050. https://doi.org/10.3390/ijms24076050
  4. Electricwala, M. (2024c, August 27). Neurotransmitters: Roles, Functions, and Impact on Mental Health. MAVE HEALTH PRIVATE LIMITED. https://www.mavehealth.com/blogs/neurotransmitters-functions-examples-disorders
  5. Grinchii, D., & Dremencov, E. (2020). Mechanism of Action of Atypical Antipsychotic Drugs in Mood Disorders. International Journal of Molecular Sciences, 21(24), 9532. https://doi.org/10.3390/ijms21249532
  6. Professional, C. C. M. (2024f, August 15). Mood Stabilizers. Cleveland Clinic. https://my.clevelandclinic.org/health/articles/mood-stabilizers
  7. Stein, D. J., Craske, M. G., Rothbaum, B. O., Chamberlain, S. R., Fineberg, N. A., Choi, K. W., De Jonge, P., Baldwin, D. S., & Maj, M. (2021). The clinical characterization of the adult patient with an anxiety or related disorder is aimed at personalization of management. World Psychiatry, 20(3), 336–356. https://doi.org/10.1002/wps.20919
  8. 20158  Mood Stabilizing Medications. (n.d.). CAMH. https://www.camh.ca/en/health-info/mental-illness-and-addiction-index/mood-stabilizing-medication
  9. Vieta, E., Ghorpade, S., Biswas, A., Sarkar, A., Phansalkar, A., & Cooper, J. (2023). Lamotrigine efficacy, safety, and tolerability for women of childbearing age with bipolar I disorder: Meta-analysis from four randomized, placebo-controlled maintenance studies. European Neuropsychopharmacology, 78, 81–92. https://doi.org/10.1016/j.euroneuro.2023.09.001
  10. Yatham, L. N., Kennedy, S. H., Parikh, S. V., Schaffer, A., Bond, D. J., Frey, B. N., Sharma, V., Goldstein, B. I., Rej, S., Beaulieu, S., Alda, M., MacQueen, G., Milev, R. V., Ravindran, A., O’Donovan, C., McIntosh, D., Lam, R. W., Vazquez, G., Kapczinski, F., . . . Berk, M. (2018). Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disorders, 20(2), 97–170. https://doi.org/10.1111/bdi.12609
  11. Image Designed by Freepik
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